Cardiology

Articles:

300 Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
https://www.pnas.org/content/118/20/e2024215118

299 SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
https://stm.sciencemag.org/content/13/590/eabf7872

298 Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
https://stm.sciencemag.org/content/13/590/eabb0602

297 Implantation of a perfusable device into the epicardium enables delivery of therapeutic agents and infiltration of reparative cells into the heart, amplifying the therapeutic effects of FGF-23 in a rat model of myocardial infarction.
https://www.nature.com/articles/s41591-021-01279-9

296 A transcription factor coordinates cardiomyocyte dedifferentiation and proliferation in adult hearts.
https://science.sciencemag.org/content/372/6538/201

295 The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
https://www.nature.com/articles/s41586-021-03341-5

294 SVEP1 is a human coronary artery disease locus that promotes atherosclerosis.
https://stm.sciencemag.org/content/13/586/eabe0357

293 Prosaposin mediates inflammation in atherosclerosis.
https://stm.sciencemag.org/content/13/584/eabe1433

292 Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates.
https://stm.sciencemag.org/content/13/584/eabb0202

291 The NAD+ precursor nicotinamide improves diastolic dysfunction caused by aging, hypertension, or metabolic syndrome in rodents.
https://stm.sciencemag.org/content/13/580/eabd7064

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