Cardiology

Articles:

307 A single-cell atlas of the heart identifies cellular interactions and pathways involved in two types of cardiomyopathy.
https://www.science.org/doi/10.1126/science.abo1984

306 Phenotypic screening with deep learning identifies HDAC6 inhibitors as cardioprotective in a BAG3 mouse model of dilated cardiomyopathy.
https://www.science.org/doi/10.1126/scitranslmed.abl5654

305 Light exposure during sleep impairs cardiometabolic function.
https://www.pnas.org/doi/10.1073/pnas.2113290119

304 CAR T cells produced in vivo to treat cardiac injury.
https://www.science.org/doi/10.1126/science.abm0594

303 Exome sequencing identifies a genetic variant with protective effects in cardiovascular disease.
https://www.science.org/doi/10.1126/science.abe0348

302 Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice.
https://www.science.org/doi/10.1126/science.abg5159

301 APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans.
https://www.nature.com/articles/s41586-021-03818-3

300 Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
https://www.pnas.org/content/118/20/e2024215118

299 SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19.
https://stm.sciencemag.org/content/13/590/eabf7872

298 Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial.
https://stm.sciencemag.org/content/13/590/eabb0602

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