Regenerative Medicine

Articles:

182 Enhancer-directed gene delivery for digit regeneration based on conserved epidermal factors
https://www.pnas.org/doi/10.1073/pnas.2532804123

181 Caspase 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis
https://www.nature.com/articles/s41586-026-10343-8

180 Hyaluronic acid and tissue mechanics orchestrate mammalian digit tip regeneration
https://www.science.org/doi/10.1126/science.ady3136

179 Species-specific oxygen sensing governs the initiation of vertebrate limb regeneration
https://www.science.org/doi/10.1126/science.adw8526

178 Inhibition of 15-hydroxy prostaglandin dehydrogenase promotes cartilage regeneration
https://www.science.org/doi/10.1126/science.adx6649

177 A glycolytic shunt via the pentose phosphate pathway is a metabolic checkpoint for nervous system sensory homeostasis and axonal regeneration
https://www.cell.com/cell/fulltext/S0092-8674(25)01379-0

176 Artificially constructed collagen-targeting receptors on mesenchymal stromal cells promote anoikis resistance and tissue repair
https://www.pnas.org/doi/10.1073/pnas.2525881123

175 A peripheral glial niche orchestrates the early stages of skin wound healing
https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(25)00449-7

174 Engineered and decellularized human cartilage graft exhibits intrinsic immunosuppressive properties and full skeletal repair capacity
https://www.pnas.org/doi/10.1073/pnas.2507185123

173 Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis
https://www.nature.com/articles/s41556-025-01804-9

172 Adrenergic signaling coordinates distant and local responses to amputation in axolotl
https://www.cell.com/cell/fulltext/S0092-8674(25)01125-0

171 Neural crest cell recruitment and reprogramming as central drivers of embryonic limb regeneration
https://www.pnas.org/doi/10.1073/pnas.2519994122

170 Molecular basis for de novo thymus regeneration in a vertebrate, the axolotl
https://www.science.org/doi/10.1126/sciimmunol.adw9903

169 Putative muscle stem cells promote Xenopus tail regeneration by modifying macrophage function via c1qtnf3
https://www.pnas.org/doi/10.1073/pnas.2504410122

168 Biomimetic supramolecular protein matrix restores structure and properties of human dental enamel
https://www.nature.com/articles/s41467-025-64982-y

167 Evidence for improved DNA repair in long-lived bowhead whale
https://www.nature.com/articles/s41586-025-09694-5

166 Deletion of murine Sarm1 results in a microenvironment that delays peripheral nerve regeneration after injury
https://www.science.org/doi/10.1126/scitranslmed.adp9155

165 Mechanical cues polarize ADIP protein complexes to control vertebrate morphogenesis and wound healing
https://www.cell.com/current-biology/fulltext/S0960-9822(25)00685-2

164 Metabolic adaptations direct cell fate during tissue regeneration
https://www.nature.com/articles/s41586-025-09097-6

163 Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair
https://www.science.org/doi/10.1126/scitranslmed.adk2101

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