1 Fibroblast growth factor-21(FGF-21) induces peroxisome proliferator-activated receptor gamma coactivator protein-1alpha modulating flux through fat oxidation, TCA cycle and gluconeogenesis. FGF-21 regulates carbohydrate and fat metabolism during the fasting to starvation phase. Potthoff et al. (2009) Proc Natl Acad Sci 106(26):10853-10858.
http://www.pnas.org/content/106/26/10853.full.pdf+html
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