153 Host–microbiome mutualism drives urea carbon salvage and acetogenesis during hibernation
https://www.pnas.org/doi/10.1073/pnas.2518978123
152 DNA damage modulates sleep drive in basal cnidarians with divergent chronotypes
https://www.nature.com/articles/s41467-025-67400-5
151 Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle–tumor metabolic competition
https://www.pnas.org/doi/10.1073/pnas.2508707122
150 Exercise suppresses DEAF1 to normalize mTORC1 activity and reverse muscle aging
https://www.pnas.org/doi/10.1073/pnas.2508893122
149 A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging.
https://www.science.org/doi/10.1126/science.adp5056
148 Life without sex: Large-scale study links sexlessness to physical, cognitive, and personality traits, socioecological factors, and DNA
https://www.pnas.org/doi/10.1073/pnas.2418257122
147 Lysosomes signal through the epigenome to regulate longevity across generations
https://www.science.org/doi/10.1126/science.adn8754
146 Inhibiting SLC38A2 lowers blood pressure in rodent models of hypertension
https://www.science.org/doi/10.1126/scitranslmed.adt5947
145 Autophagy activator AA-20 improves proteostasis and extends Caenorhabditis elegans lifespan
https://www.pnas.org/doi/10.1073/pnas.2423455122
144 Acyl-CoA-binding protein as a driver of pathological aging
https://www.pnas.org/doi/10.1073/pnas.2501584122
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