11 Normal gut microbiota modulates brain development and behavior. Heijtz RD et al. (2011). PNAS 108:3047-3052.
http://www.pnas.org/content/108/7/3047.abstract
10 Exercise training increases size of hippocampus and improves memory. Erickson KI et al. (2011). PNAS 108:3017-3022.
http://www.pnas.org/content/108/7/3017.abstract
9 Identification of a brain center whose activity discriminates a choice behavior in zebrafish.
Lau BYB. (2011). PNAS 108:2581-2586.
http://www.pnas.org/content/108/6/2581.abstract
8 In the rat, administering insulin-like growth factor II (IGF-II, also known as IGF2) significantly enhances memory retention and prevents forgetting. Chen DY, et al. (2011). Nature 469:491-497.
http://www.nature.com/nature/journal/v469/n7331/full/nature09667.html
7 Role of infiltrating monocyte-derived macrophages in neuroprotection and progenitor cell renewal in the injured retina, with far-reaching potential implications to retinal neuropathies and other neurodegenerative disorders. London A, et al. (2011). Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.JEM 208:23-39.
http://jem.rupress.org/content/208/1/23.abstract
6 Alzheimer’s disease is associated with reduced β-amyloid clearance from the brain
Mawuenyega KG, et al. (2010). Decreased clearance of CNS β-Amyloid in Alzheimer’s disease. Science 330: 1774
http://www.sciencemag.org/content/330/6012/1774.abstract
5 The intracerebral injection of β-amyloid–containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. Intraperitoneal inoculation with β-amyloid–rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times.
Eisele YS, et al. (2010) Science 330: 980 – 982.
http://www.sciencemag.org/cgi/content/abstract/330/6006/980
4 Adult microglia derive from primitive macrophages.
Ginhoux F, et al. (2010). Science 330: 841 – 845.
http://www.sciencemag.org/cgi/content/abstract/330/6005/841
3 Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in alzheimer's disease.
Duce JA. et al. (2010). Cell 142: 857-867.
http://www.cell.com/abstract/S0092-8674(10)00938-4
2 KHS101 accelerates neuronal differentiation by interaction with TACC3 and may provide a basis for pharmacological intervention directed at endogenous neural progenitor cells.
Wurdak H. et al. (2010) PNAS 107: 16542-16547.
http://www.pnas.org/content/107/38/16542.abstract
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