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Neuroscience

Neuroscience

Articles:

6  Alzheimer’s disease is associated with reduced β-amyloid clearance from the brain Mawuenyega KG, et al. (2010). Decreased clearance of CNS β-Amyloid in Alzheimer’s disease. Science 330: 1774
http://www.sciencemag.org/content/330/6012/1774.abstract

5  The intracerebral injection of β-amyloid–containing brain extracts can induce cerebral β-amyloidosis and associated pathologies in susceptible hosts. Intraperitoneal inoculation with β-amyloid–rich extracts induced β-amyloidosis in the brains of β-amyloid precursor protein transgenic mice after prolonged incubation times. Eisele YS, et al. (2010) Science 330: 980 – 982.
http://www.sciencemag.org/cgi/content/abstract/330/6006/980

4  Adult microglia derive from primitive macrophages. Ginhoux F, et al. (2010). Science 330: 841 – 845.
http://www.sciencemag.org/cgi/content/abstract/330/6005/841

3  Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in alzheimer's disease. Duce JA. et al. (2010). Cell 142: 857-867.
http://www.cell.com/abstract/S0092-8674(10)00938-4

2  KHS101 accelerates neuronal differentiation by interaction with TACC3 and may provide a basis for pharmacological intervention directed at endogenous neural progenitor cells. Wurdak H. et al. (2010) PNAS 107: 16542-16547.
http://www.pnas.org/content/107/38/16542.abstract

1  Gamma-secretase activating protein is a therapeutic target for Alzheimer’s disease He G. et al. (2010). Nature 467: 95-98.
http://www.nature.com/nature/journal/v467/n7311/abs/nature09325.html

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