682 A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging
https://www.science.org/doi/10.1126/science.adp5056
681 A circularly permuted CasRx platform for efficient, site-specific RNA editing
https://www.nature.com/articles/s41587-024-02430-w
680 A general genome editing strategy using CRISPR lipid nanoparticle spherical nucleic acids
https://www.pnas.org/doi/10.1073/pnas.2426094122
679 Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein
https://www.nature.com/articles/s41587-024-02437-3
678 Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
https://www.cell.com/cell/fulltext/S0092-8674(25)00619-1
677 A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy
https://www.science.org/doi/10.1126/science.adp5384
676 A DNA-gated molecular guard controls bacterial Hailong anti-phage defence
https://www.nature.com/articles/s41586-025-09058-z
675 A noncanonical cGAS–STING pathway drives cellular and organismal aging
https://www.pnas.org/doi/10.1073/pnas.2424666122
674 An enzyme-based approach for highly efficient self-replication of DNA origami dimers
https://www.pnas.org/doi/10.1073/pnas.2500160122
673 Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin
https://www.science.org/doi/10.1126/science.adr9097
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