435 Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome.
https://www.nature.com/articles/s41591-021-01262-4
434 A modified antisense oligonucleotide that blocks pathogenic splicing of progeria transcripts reduces the production of progerin in key target organs and extends animal lifespan in mouse model of progeria syndrome.
https://www.nature.com/articles/s41591-021-01274-0
433 Genomic insights into the formation of human populations in East Asia.
https://www.nature.com/articles/s41586-021-03336-2
432 Patterns of de novo tandem repeat mutations and their role in autism.
https://www.nature.com/articles/s41586-020-03078-7
431 Sequence diversity analyses of an improved rhesus macaque genome enhance its biomedical utility.
https://science.sciencemag.org/content/370/6523/eabc6617
430 High-depth African genomes inform human migration and health.
https://www.nature.com/articles/s41586-020-2859-7
429 Evidence for 28 genetic disorders discovered by combining healthcare and research data.
https://www.nature.com/articles/s41586-020-2832-5
428 The mouse Sry locus harbors a cryptic exon that is essential for male sex determination.
https://science.sciencemag.org/content/370/6512/121
427 Genome-wide detection of tandem DNA repeats that are expanded in autism.
https://www.nature.com/articles/s41586-020-2579-z
426 Selection after admixture resulted in the human Y chromosome replacing the archaic Y of Neanderthals.
https://science.sciencemag.org/content/369/6511/1653
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