25 High Resolution In Vivo Bioluminescent Imaging for the Study of Bacterial Tumour Targeting.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0030940
24 The sequencing of AML genomes of eight patients before and after relapse reveals two major patterns of clonal evolution, with chemotherapy appearing to have a role in both patterns.
http://www.nature.com/nature/journal/v481/n7382/full/nature10738.html
23 EMT and Dissemination Precede Pancreatic Tumor Formation.
http://www.cell.com/abstract/S0092-8674(11)01369-9
22 An RNA interference screen identifies a “druggable” enzyme whose inhibition halts tumor cell growth.
http://www.sciencemag.org/content/335/6066/348.abstract
21 Reductive carboxylation supports growth in tumour cells with defective mitochondria.
http://www.nature.com/nature/journal/v481/n7381/full/nature10642.html
20 The retinoblastoma genome is shown to be stable, but multiple cancer pathways are identified that are epigenetically deregulated, providing potential new therapeutic targets.
http://www.nature.com/nature/journal/v481/n7381/full/nature10733.html
19 The microRNA miR-126 suppresses the formation of breast cancer metastases via the suppression of several novel pro-angiogenic genes that cooperate in the recruitment of endothelial cells, leading to the formation of metastatic colonies.
http://www.nature.com/nature/journal/v481/n7380/full/nature10661.html
18 Epigenetic Changes of CXCR4 and Its Ligand CXCL12 as Prognostic Factors for Sporadic Breast Cancer.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029461
17 The functional crosstalk between Wnt/β-catenin and BRAF signaling may yield more effective therapies for treating melanoma.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/206/ra3
16 2-Hydroxyglutarate, a metabolite overproduced in IDH-mutated gliomas, can be detected noninvasively in patients with brain tumors by optimized magnetic resonance spectroscopy.
http://stm.sciencemag.org/content/4/116/116ra4.abstract
15 Pertuzumab plus Trastuzumab plus Docetaxel for Metastatic Breast Cancer.
http://www.nejm.org/doi/full/10.1056/NEJMoa1113216
14 Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells.
http://www.pnas.org/content/109/2/419.abstract
13 Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis.
http://bloodjournal.hematologylibrary.org/content/119/1/115.abstract
12 AAV8 vector expressing IL24 efficiently suppresses tumor growth mediated by specific mechanisms in MLL/AF4-positive ALL model mice.
http://bloodjournal.hematologylibrary.org/content/119/1/64.abstract
11 Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029770
10 Interactions between cancer stem cells and their niche govern metastatic colonization.
http://www.nature.com/nature/journal/v481/n7379/full/nature10694.html
9 Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
http://www.nature.com/nm/journal/v17/n12/abs/nm.2536.html
8 Molecular classification of prostate cancer using curated expression signatures.
http://www.pnas.org/content/108/52/21276.abstract
7 Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells.
http://www.pnas.org/content/108/51/E1408.abstract
6 Regulation of Cysteinyl Leukotriene Receptor 2 Expression—A Potential Anti-Tumor Mechanism.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029060
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