385 Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
http://jem.rupress.org/content/211/3/473.abstract
384 Interplay of host microbiota, genetic perturbations, and inflammation promotes local development of intestinal neoplasms in mice.
http://jem.rupress.org/content/211/3/457
383 2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.
http://www.nature.com/ncomms/2014/140312/ncomms4459/full/ncomms4459.html
382 ATP-triggered anticancer drug delivery.
http://www.nature.com/ncomms/2014/140311/ncomms4364/full/ncomms4364.html
381 Guiding intracortical brain tumour cells to an extracortical cytotoxic hydrogel using aligned polymeric nanofibres.
http://www.nature.com/nmat/journal/v13/n3/full/nmat3878.html
380 Circulating giant macrophages as a potential biomarker of solid tumors.
http://www.pnas.org/content/111/9/3514.abstract
379 Mouse experiments show that ultraviolet radiation can promote tumour metastasis in melanoma by enhancing the expansion of tumour cells on blood vessel surfaces in a process linked to inflammation and requiring neutrophils and the proteins HMGB1 and TLR4.
http://www.nature.com/nature/journal/v507/n7490/full/nature13111.html
378 Intratumoral treatment with an oncolytic virus results in inflammatory infiltrates in distant tumors and sensitizes the tumors to immune-mediated rejection in the setting of immunotherapy with CTLA-4 blocking antibodies.
http://stm.sciencemag.org/content/6/226/226ra32.abstract
377 Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention.
http://www.pnas.org/content/111/8/3020.abstract
376 A rare form of liver cancer affecting young adults expresses a chimeric kinase that may contribute to pathogenesis.
http://www.sciencemag.org/content/343/6174/1010.abstract
375 CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients.
http://stm.sciencemag.org/content/4/134/134ra62.abstract
374 β-Catenin Promotes Colitis and Colon Cancer Through Imprinting of Proinflammatory Properties in T Cells.
http://stm.sciencemag.org/content/6/225/225ra28
373 Colorectal cancers that become resistant to EGFR inhibitors through a variety of mechanisms can be effectively treated by inhibiting MEK in conjunction with EGFR.
http://stm.sciencemag.org/content/6/224/224ra26.abstract
372 Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia.
http://www.nature.com/nature/journal/v506/n7488/full/nature13038.html
371 Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.
http://www.nature.com/ncomms/2014/140218/ncomms4295/full/ncomms4295.html
370 Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia.
http://www.nature.com/ncomms/2014/140218/ncomms4273/full/ncomms4273.html
369 In vivo discovery of immunotherapy targets in the tumour microenvironment.
http://www.nature.com/nature/journal/v506/n7486/full/nature12988.html
368 The antioxidants acetylcysteine and vitamin E accelerate tumor progression and reduce survival in mouse models of lung cancer by disrupting the ROS-p53 axis.
http://stm.sciencemag.org/content/6/221/221ra15.abstract
367 GRK3 is essential for metastatic cells and promotes prostate tumor progression.
http://www.pnas.org/content/111/4/1521.abstract
366 TRAIL-coated leukocytes that kill cancer cells in the circulation.
http://www.pnas.org/content/111/3/930.abstract
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