937 Enhanced Transdermal Drug Delivery by Transfersome-Embedded Oligopeptide Hydrogel for Topical Chemotherapy of Melanoma.
https://pubs.acs.org/doi/10.1021/acsnano.8b03800
936 Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
http://stm.sciencemag.org/content/10/464/eaat3487
935 Chromatin accessibility profiling identifies principles of epigenetic regulation in 23 primary human cancers.
http://science.sciencemag.org/content/362/6413/eaav1898
934 Decreased abundance of TRESK two-pore domain potassium channels in sensory neurons underlies the pain associated with bone metastasis.
http://stke.sciencemag.org/content/11/552/eaao5150
933 Local generation of hydrogen for enhanced photothermal therapy.
https://www.nature.com/articles/s41467-018-06630-2
932 BAP1 links metabolic regulation of ferroptosis to tumour suppression.
https://www.nature.com/articles/s41556-018-0178-0
931 Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy.
http://science.sciencemag.org/content/362/6411/eaar3593
930 SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer.
https://www.cell.com/immunity/fulltext/S1074-7613(18)30387-X
929 The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells.
https://www.cell.com/immunity/fulltext/S1074-7613(18)30381-9
928 Prostate and lung cancers convert to a drug-resistant, lethal form of cancer through the same reprogramming mechanism.
http://science.sciencemag.org/content/362/6410/91
927 Two Patched molecules engage distinct sites on Hedgehog yielding a signaling-competent complex.
http://science.sciencemag.org/content/362/6410/eaas8843
926 Necroptosis microenvironment directs lineage commitment in liver cancer.
https://www.nature.com/articles/s41586-018-0519-y
925 Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice.
http://science.sciencemag.org/content/361/6409/eaao4227
924 mRNA vaccination with charge-altering releasable transporters elicits human T cell responses and cures established tumors in mice.
http://www.pnas.org/content/115/39/E9153
923 Precancerous neoplastic cells can move through the pancreatic ductal system.
https://www.nature.com/articles/s41586-018-0481-8
922 Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.
https://www.cell.com/cell/fulltext/S0092-8674(18)30913-9
921 Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids.
https://www.cell.com/cell/fulltext/S0092-8674(18)30903-6
920 Genotype-targeted local therapy of glioma.
http://www.pnas.org/content/115/36/E8388
919 Classification of prostate cancer using a protease activity nanosensor library.
http://www.pnas.org/content/115/36/8954
918 The gene fusions driving sarcoma growth often arise by the formation of dramatic genomic loops that rearrange many genes.
http://science.sciencemag.org/content/361/6405/eaam8419
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