78 JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function.
https://stm.sciencemag.org/content/12/530/eaay4447
77 Oxytocin regulates body composition.
https://www.pnas.org/content/116/52/26808
76 Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE).
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)32489-4/fulltext
75 Study shows the repair of enamel via a biomimetic growth frontier that is constructed from calcium phosphate ion clusters.
https://advances.sciencemag.org/content/5/8/eaaw9569
74 Locally renewing resident synovial macrophages provide a protective barrier for the joint.
https://www.nature.com/articles/s41586-019-1471-1
73 Prominent exostosis projecting from the occipital squama more substantial and prevalent in young adult than older age groups.
https://www.nature.com/articles/s41598-018-21625-1
72 A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
https://stm.sciencemag.org/content/11/489/eaar4953
71 Biomaterials-aided mandibular reconstruction using in vivo bioreactors.
https://www.pnas.org/content/116/14/6954
70 Oral versus Intravenous Antibiotics for Bone and Joint Infection.
https://www.nejm.org/doi/full/10.1056/NEJMoa1710926
69 Increased glutamine metabolism caused by unregulated HIF-1α signalling in mouse chondrocytes results in increased post-translational modification of collagen and skeletal dysplasia, demonstrating that strict regulation of HIF-1α signalling in chondrocytes is essential for normal bone growth.
https://www.nature.com/articles/s41586-019-0874-3
68 Deep neural network improves fracture detection by clinicians.
http://www.pnas.org/content/115/45/11591
67 ANP32A regulates ATM expression and prevents oxidative stress in cartilage, brain, and bone.
http://stm.sciencemag.org/content/10/458/eaar8426
66 Risk factors associated with revision for prosthetic joint infection after hip replacement: a prospective observational cohort study.
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(18)30345-1/fulltext
65 Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial.
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)32137-2/fulltext
64 Mechanobiologically optimized 3D titanium-mesh scaffolds enhance bone regeneration in critical segmental defects in sheep.
http://stm.sciencemag.org/content/10/423/eaam8828
63 C-reactive protein promotes bone destruction in human myeloma through the CD32–p38 MAPK–Twist axis.
http://stke.sciencemag.org/content/10/509/eaan6282
62 Romosozumab or Alendronate for Fracture Prevention in Women with Osteoporosis.
http://www.nejm.org/doi/full/10.1056/NEJMoa1708322
61 Plasmodium products persist in the bone marrow and promote chronic bone loss.
http://immunology.sciencemag.org/content/2/12/eaam8093
60 In vivo engineering of bone tissues with hematopoietic functions and mixed chimerism.
http://www.pnas.org/content/114/21/5419.abstract
59 In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs.
http://stm.sciencemag.org/content/9/390/eaal3128
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