19 Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Sekiya S and Suzuki A. (2011). Nature 475:390-393.
http://www.nature.com/nature/journal/v475/n7356/full/nature10263.html
18 Proteins are identified that underlie the early commitment steps of human hematopoietic stem cell differentiation. Notta F. et al. (2011). Science 333:218-221.
http://www.sciencemag.org/content/333/6039/218.abstract
17 Krencik et al. present a chemically defined system for differentiating human pluripotent stem cells to large numbers of immature astrocytes, which mature further after transplantation to the neonatal mouse brain. By applying regional patterning factors at the neuroepithelial stage, the authors also succeed in generating different astrocytes subtypes. Krencik R. et al. (2011). Nature Biotechnology 29:528–534.
http://www.nature.com/nbt/journal/v29/n6/abs/nbt.1877.html
16 Immunogenicity of induced pluripotent stem cells. Zhao T et al. (2011). Nature 474: 212-215.
http://www.nature.com/nature/journal/v474/n7350/full/nature10135.html
15 Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Maekawa M. et al. (2011). Nature 474:225-229.
http://www.nature.com/nature/journal/v474/n7350/full/nature10106.html
14 Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.Batista LFC. et al. (2011). Nature 474:399–402.
http://www.nature.com/nature/journal/v474/n7351/full/nature10084.html
13 Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome. Liu GH et al.(2011). Nature 472:221–225.
http://www.nature.com/nature/journal/v472/n7342/full/nature09879.html
12 Mouse embryonic stem cells can successfully organize themselves into a layered structure resembling the optic cup, that develops into the inner and outer layers of the retina during embryogenesis. Eiraku M. et al. (2011) Nature 472: 51–56.
http://www.nature.com/nature/journal/v472/n7341/full/nature09941.html
11 In vitro production of functional sperm in cultured neonatal mouse testes. Sato T. et al. (2011). Nature 471:504–507.
http://www.nature.com/nature/journal/v471/n7339/full/nature09850.html
10 The heart in a newborn mouse can rebuild itself after injury, but this regenerative capacity is lost within a few days.
Porrello ER et al. (2011) Science 331: 1078-1080.
http://www.sciencemag.org/content/331/6020/1078.abstract
|
