212 Vascularized, functional human liver is generated from human induced pluripotent stem cells (iPSCs) by transplantation of liver buds created in vitro (iPSC-LBs); hepatic cells self-organized into three-dimensional iPSC-LBs, and human vasculatures in iPSC-LB transplants became functional by connecting to host vessels, stimulating maturation of iPSC-LBs into tissue resembling adult liver and performing liver-specific functions.
http://www.nature.com/nature/journal/v499/n7459/full/nature12271.html
211 Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts.
http://www.pnas.org/content/110/30/12172.abstract
210 Elimination of a proapoptotic gene increases hair follicle stem cells and improves skin regeneration and wound repair in mice.
http://www.sciencemag.org/content/341/6143/286.abstract
209 Nail stem cells (NSCs) reside in the proximal nail matrix, and early nail progenitors undergo Wnt-dependent differentiation into the nail; after amputation, Wnt activation is required for nail and digit regeneration, and amputations proximal to the Wnt-active nail progenitors fail to regenerate, but β-catenin stabilization in the NSC region induces regeneration.
http://www.nature.com/nature/journal/v499/n7457/full/nature12214.html
208 High-resolution analysis with novel cell-surface markers identifies routes to iPS cells.
http://www.nature.com/nature/journal/v499/n7456/full/nature12243.html
207 Bioactive Silicate Nanoplatelets for Osteogenic Differentiation of Human Mesenchymal Stem Cells.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201300584/abstract
206 Induced Pluripotent Stem Cell-Derived Cardiac Progenitors Differentiate to Cardiomyocytes and Form Biosynthetic Tissues.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0065963
205 Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells.
http://www.nature.com/srep/2013/130613/srep01978/full/srep01978.html
204 Eosinophils secrete IL-4 to facilitate liver regeneration.
http://www.pnas.org/content/110/24/9914.abstract
203 Epithelial neoplasia in Drosophila entails switch to primitive cell states.
http://www.pnas.org/content/110/24/E2163.abstract
|