Regenerative Medicine

Articles:

98 Single-cell-based imaging and sequencing approaches are used to characterize organoid development and the intestinal regeneration process, which is driven by transient activation of YAP1.
https://www.nature.com/articles/s41586-019-1146-y

97 A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix.
https://stm.sciencemag.org/content/11/489/eaar4953

96 Bioengineered human acellular vessels repopulate with host cells and evolve into self-sustaining living blood vessels in hemodialysis patients.
http://stm.sciencemag.org/content/11/485/eaau6934

95 The genome of the acoel worm Hofstenia miamia elucidates a gene regulatory network that underlies the ability to regenerate.
http://science.sciencemag.org/content/363/6432/eaau6173

94 Phosphate graphene as an intrinsically osteoinductive scaffold for stem cell-driven bone regeneration.
https://www.pnas.org/content/116/11/4855

93 Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair.
https://www.nature.com/articles/s41467-019-09046-8

92 A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration.
https://www.cell.com/cell/fulltext/S0092-8674(18)31637-4

91 Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability.
https://www.pnas.org/content/116/9/3614

90 ABL kinase inhibition promotes lung regeneration through expansion of an SCGB1A1+ SPC+ cell population following bacterial pneumonia.
https://www.pnas.org/content/116/5/1603

89 Impaired immune surveillance accelerates accumulation of senescent cells and aging.
https://www.nature.com/articles/s41467-018-07825-3#ref-CR67

88 During skin repair, macrophages activate proliferation of a myofibroblast subset that can form adipocytes and promote dermal repair.
http://science.sciencemag.org/content/362/6417/eaar2971

87 Reversion of adult skeletal stem cells to a developmental state underlies the growth of new bone during jaw regeneration, in a process that relies on mechanotransduction via the focal adhesion kinase protein.
https://www.nature.com/articles/s41586-018-0650-9

86 Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins.
https://www.sciencedirect.com/science/article/pii/S2211124718315687

85 Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb.
https://www.sciencedirect.com/science/article/pii/S2211124718315730?via%3Dihub

84 Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration.
http://science.sciencemag.org/content/362/6413/eaaq0681

83 Regnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolism.
http://www.pnas.org/content/115/43/11036

82 Thyroid hormone signaling specifies cone subtypes in human retinal organoids.
http://science.sciencemag.org/content/362/6411/eaau6348

81 ITGBL1 promotes chondrogenesis and protects joint cartilage from osteoarthritis by inhibiting integrin-extracellular matrix interaction.
http://stm.sciencemag.org/content/10/462/eaam7486

80 Mechanosensing by β1 integrin induces angiocrine signals for liver growth and survival.
https://www.nature.com/articles/s41586-018-0522-3

79 In vivo reprogramming of wound-resident cells generates skin epithelial tissue.
https://www.nature.com/articles/s41586-018-0477-4

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