126 Human-relevant levels of added sugar consumption increase female mortality and lower male fitness in mice.
http://www.nature.com/ncomms/2013/130813/ncomms3245/full/ncomms3245.html
125 The impact of sleep deprivation on food desire in the human brain.
http://www.nature.com/ncomms/2013/130806/ncomms3259/full/ncomms3259.html
124 Metformin improves healthspan and lifespan in mice.
http://www.nature.com/ncomms/2013/130730/ncomms3192/full/ncomms3192.html
123 Reprogramming of Intestinal Glucose Metabolism and Glycemic Control in Rats After Gastric Bypass.
http://www.sciencemag.org/content/341/6144/406.abstract
122 A study in zebrafish sheds light on the signaling properties of a protein implicated in severe obesity in mice.
http://www.sciencemag.org/content/341/6143/278.abstract
121 Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity.
http://www.sciencemag.org/content/341/6143/275.abstract
120 Structural modulation of gut microbiota in life-long calorie-restricted mice.
http://www.nature.com/ncomms/2013/130716/ncomms3163/full/ncomms3163.html
119 Obesity is shown in a mouse model of liver cancer to strongly enhance tumorigenesis; a high fat diet alters the composition of intestinal bacteria, leading to more production of the metabolite DCA which, probably together with other factors, induces senescence and the secretion of various senescence-associated cytokines in hepatic stellate cells, thus promoting cancer.
http://www.nature.com/nature/journal/v499/n7456/full/nature12347.html
118 A pair of Drosophila brain cells is identified and its activation alone is found to induce the fly’s complete feeding motor routine when artificially induced; suppressing or ablating these two neurons eliminates the sugar-induced feeding behaviour, but ablation of just one neuron results in asymmetric movements.
http://www.nature.com/nature/journal/v499/n7456/full/nature12208.html
117 Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice.
http://www.pnas.org/content/110/26/10759.abstract
|