976 Mouse models of Alzheimer’s disease show reduced, behaviourally driven gamma oscillations before the onset of plaque formation or cognitive decline; driving neurons to oscillate at gamma frequency (40 Hz) reduces levels of amyloid-β peptides.
http://www.nature.com/nature/journal/v540/n7632/full/nature20587.html
975 Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson’s disease.
http://stm.sciencemag.org/content/8/368/368ra174
974 Midbrain dopamine neurons control judgment of time.
http://science.sciencemag.org/content/354/6317/1273
973 Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease.
http://www.cell.com/cell/abstract/S0092-8674(16)31590-2
972 Cannabinoids affect CB1 receptors on the mitochondrial membranes in the brain, triggering a decrease in downstream cAMP-dependent signalling; this leads to a decrease in brain mitochondrial activity and to cannabinoid-induced amnesia.
http://www.nature.com/nature/journal/v539/n7630/full/nature20127.html
971 Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.
http://www.cell.com/neuron/fulltext/S0896-6273(16)30581-5
970 The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS.
http://www.cell.com/neuron/fulltext/S0896-6273(16)30585-2
969 Molecular and Neural Functions of Rai1, the Causal Gene for Smith-Magenis Syndrome.
http://www.cell.com/neuron/fulltext/S0896-6273(16)30578-5
968 Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice.
http://science.sciencemag.org/content/354/6314/904
967 Forward-genetics analysis of sleep in randomly mutagenized mice.
http://www.nature.com/nature/journal/v539/n7629/full/nature20142.html
|