186 Male mice that overexpress SIRT6 are shown to have a longer lifespan than wild-type mice, unlike their female counterparts.
http://www.nature.com/nature/journal/v483/n7388/full/nature10815.html
185 Tat-NR2B9c, a PSD-95 inhibitor, is shown to reduce stroke-induced behavioural and neuroanatomical deficits in cynomolgous macaques when administered in the presence of an ischemic penumbra, suggesting the potential of PSD-95 inhibition as a neuroprotectant strategy for clinical investigation.
http://www.nature.com/nature/journal/v483/n7388/full/nature10841.html
184 Cultured cerebral cortex neurons generated from human Down syndrome induced pluripotent stem cells rapidly develop Alzheimer’s disease pathologies.
http://stm.sciencemag.org/content/4/124/124ra29.abstract
183 Cylindrin from the amyloid-forming protein αB crystallin represents an amyloid oligomer.
http://www.sciencemag.org/content/335/6073/1228.abstract
182 Lithium enhances remyelination of peripheral nerves.
http://www.pnas.org/content/109/10/3973.abstract
181 Autoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processing.
http://www.pnas.org/content/109/10/3802.abstract
180 Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.
http://www.nature.com/nm/journal/v18/n2/abs/nm.2613.html
179 N-acetyl serotonin derivatives as potent neuroprotectants for retinas.
http://www.pnas.org/content/109/9/3540.abstract
178 Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.
http://www.pnas.org/content/109/9/3213.abstract
177 Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum.
http://www.pnas.org/content/109/9/E563.abstract
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