226 Molecular inhibitors of amyloid formation could help combat Alzheimer's disease, type 2 diabetes, and other major human diseases. Here, two-dimensional infrared spectroscopy and residue-specific isotope labelling are used to obtain detailed structural information on amyloid-inhibitor complexes. The unexpected behaviour observed helps to explain the moderate activity of the inhibitor studied.
http://www.nature.com/nchem/journal/v4/n5/abs/nchem.1293.html
225 Restoration of vision after transplantation of photoreceptors.
http://www.nature.com/nature/journal/v485/n7396/full/nature10997.html
224 Autism-like behaviors in mice were reversed by a negative modulator of a metabotropic glutamate receptor, suggesting a treatment for symptoms of autism spectrum disorders.
http://stm.sciencemag.org/content/4/131/131ra51.abstract
223 Neural basis of egalitarian behavior.
http://www.pnas.org/content/109/17/6479.abstract
222 Acute Leptin Treatment Enhances Functional Recovery after Spinal Cord Injury.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035594
221 Diammonium Glycyrrhizinate Upregulates PGC-1α and Protects against Aβ1–42-Induced Neurotoxicity.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035823
220 Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034024
219 High-Throughput Single-Cell Manipulation in Brain Tissue.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0035603
218 Selective Regulation of NR2B by Protein Phosphatase-1 for the Control of the NMDA Receptor in Neuroprotection.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034047
217 Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model.
http://stm.sciencemag.org/content/4/130/130ra46.abstract
|
