370 High-resolution imaging has traditionally required thin sectioning, a process that disrupts long-range connectivity in the case of brains: here, intact mouse brains and human brain samples have been made fully transparent and macromolecule permeable using a new method termed CLARITY, which allows for intact-tissue imaging as well as repeated antibody labelling and in situ hybridization of non-sectioned tissue.
http://www.nature.com/nature/journal/v497/n7449/full/nature12107.html
369 Inhibiting NMDA receptor function in the insular cortex may prevent the development of neuropathic pain.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/275/ra34
368 Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration.
http://www.pnas.org/content/110/19/7778
367 Generation of oligodendroglial cells by direct lineage conversion.
http://www.nature.com/nbt/journal/v31/n5/abs/nbt.2564.html
366 Human embryonic stem cells differentiated to medial ganglionic eminence–like cells ameliorate learning and memory deficits in a mouse model.
http://www.nature.com/nbt/journal/v31/n5/abs/nbt.2565.html
365 Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
http://www.nature.com/nbt/journal/v31/n5/full/nbt.2561.html
364 Blocking nuclear calcium signaling reversibly inhibits long-term memory formation in flies.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/274/ra33
363 Neural Decoding of Visual Imagery During Sleep.
http://www.sciencemag.org/content/340/6132/639.abstract
362 Dopamine restores reward prediction errors in old age.
http://www.nature.com/neuro/journal/v16/n5/abs/nn.3364.html
361 Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.
http://www.nature.com/neuro/journal/v16/n5/abs/nn.3356.html
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