554 Structurally polymorphic C9orf72 hexanucleotide repeats cause an impairment in transcriptional processivity and lead to accumulation of truncated repeat-containing transcripts that bind to specific ribonucleoproteins, such as nucleolin, in a conformation-dependent manner resulting in nucleolar stress and C9orf72-linked pathology in amyotrophic lateral sclerosis and frontotemporal dementia.
http://www.nature.com/nature/journal/v507/n7491/full/nature13124.html
553 The stumble gene in flies is required in neurons that sense joint angles.
http://www.sciencemag.org/content/343/6176/1256.abstract
552 Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer’s disease.
http://www.nature.com/ncomms/2014/140306/ncomms4443/full/ncomms4443.html
551 A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1S4 Gating Domain.
http://www.cell.com/current-biology/abstract/S0960-9822(14)00014-1
550 Voice-Sensitive Regions in the Dog and Human Brain Are Revealed by Comparative fMRI.
http://www.cell.com/current-biology/abstract/S0960-9822(14)00123-7
549 Phonetic Feature Encoding in Human Superior Temporal Gyrus.
http://www.sciencemag.org/content/343/6174/1006.abstract
548 In vivo conversion of astrocytes to neurons in the injured adult spinal cord.
http://www.nature.com/ncomms/2014/140225/ncomms4338/full/ncomms4338.html
547 Activity-Driven Local ATP Synthesis Is Required for Synaptic Function.
http://www.cell.com/abstract/S0092-8674(14)00013-0
546 Cholinergic activation of somatostatin-positive hippocampal CA1 interneurons promotes fear-context associations.
http://www.sciencemag.org/content/343/6173/857.abstract
545 A cortical–spinal prosthesis for targeted limb movement in paralysed primate avatars.
http://www.nature.com/ncomms/2014/140218/ncomms4237/full/ncomms4237.html
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