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Molecular Biology

Molecular Biology

Articles:

26  miR-34a regulates progenitor and metastatic properties of prostate cancer cells, and they identify CD44 as a relevant target of the microRNA. The inhibition of metastasis observed after systemic delivery of miR-34a suggests that it could be used as a potential therapeutic agent in prostate cancer. Liu et al. (2011). Nature Medicine 17:211–215
http://www.nature.com/nm/journal/v17/n2/abs/nm.2284.html

25  Identification of aneuploidy-selective antiproliferation compounds. Tang Y-C, et al. (2011). Cell 144:499-512.
http://www.cell.com/abstract/S0092-8674(11)00056-0

24  Cells respond to mechanical stress by rapid disassembly of caveolae. Sinha B. et al. (2011). Cell 144: 402-413.
http://www.cell.com/abstract/S0092-8674(10)01523-0

23  Mutant proteins as cancer-specific biomarkers. Wang Q, et al. (2011). PNAS 108:2444-2449.
http://www.pnas.org/content/108/6/2444.abstract

22  Multistage nanoparticle delivery system for deep penetration into tumor tissue. Wong C. et al. (2011). PNAS 108:2426-2431.
http://www.pnas.org/content/108/6/2426.abstract

21  miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells. Kuhn S, et al. (2011). PNAS 108: 2355-2360.
http://www.pnas.org/content/108/6/2355.abstract

20  Transgenic birds expressing a short hairpin RNA that blocks viral polymerase hinder influenza transmission.
http://www.sciencemag.org/content/331/6014/223.abstract

19  The transition from androgen-dependent to castration-resistant prostate cancer is a lethal event. N-cadherin seems to be a major cause underlying this transition, and targeting this adhesion molecule may have positive clinical benefit. Tanaka H, et al. (2010). Nature Medicine 16:1414–1420.
http://www.nature.com/nm/journal/v16/n12/abs/nm.2236.html

18  Chemical synthesis of the mouse mitochondrial genome. Gibson DG et al. (2010). Nature Methods 7: 901-903.
http://www.nature.com/nmeth/journal/v7/n11/abs/nmeth.1515.html

17  A eukaryotic protein complex helps detect and destroy "aberrant" messenger RNAs stalled on ribosomes. Shoemaker CJ, et al. (2010) Science 330: 369-372.
http://www.sciencemag.org/cgi/content/abstract/330/6002/369

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