209 NAD-dependent deacetylase SIRT2 is an essential component of necrosis, and that mouse hearts that do not contain SIRT2 or that are treated with a pharmacological inhibitor of SIRT2 are largely protected from ischaemic injury.
http://www.nature.com/nature/journal/v492/n7428/full/nature11700.html
208 Transporting lipopolysaccharide from inside the bacterial cell to the surface requires multiple molecules of adenosine triphosphate.
http://www.sciencemag.org/content/338/6111/1214.abstract
207 On application of a focused magnetic field, zinc-doped iron oxide nanoparticles with targeting antibodies attached are shown to activate cell death signalling in a spatially controlled manner. This triggering of apoptosis signalling, via the magnetically activated aggregation of receptors, is observed in both in vitro and in vivo systems.
http://www.nature.com/nmat/journal/v11/n12/abs/nmat3430.html
206 A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation.
http://www.pnas.org/content/109/47/19351.abstract
205 Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.
http://www.nature.com/nature/journal/v491/n7425/full/nature11536.html
204 Principles for designing ideal protein structures. Koga N. et al. (2012). Nature 491:222-227.
http://www.nature.com/nature/journal/v491/n7423/full/nature11600.html
203 Ultrahigh-resolution X-ray crystallography study of a phosphate-binding protein from Pseudomonas fluorescens yields insight into how phosphate ions essential for life are discriminated from the arsenate ions inimical to it, even in arsenate-rich environments.
http://www.nature.com/nature/journal/v491/n7422/full/nature11517.html
202 In vivo genome editing using a high-efficiency TALEN system.
http://www.nature.com/nature/journal/v491/n7422/full/nature11537.html
201 Single-Stranded siRNAs Activate RNAi in Animals.
http://www.cell.com/abstract/S0092-8674(12)01009-4
200 Drosophila Auditory Organ Genes and Genetic Hearing Defects.
http://www.cell.com/abstract/S0092-8674(12)00926-9
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