406 The structure of the Cas1–Cas2 complex bound to a protospacer sequence illustrates how foreign DNA is captured and measured by bacterial proteins in preparation for integration into CRISPR loci.
http://www.nature.com/nature/journal/v527/n7579/full/nature15760.html
405 CRISPR-Cas genome editing is adapted to remove 62 copies of a retrovirus from the porcine genome.
http://www.sciencemag.org/content/350/6264/1101.abstract
404 SUMOylation of TARBP2 regulates miRNA/siRNA efficiency.
http://www.nature.com/ncomms/2015/151119/ncomms9899/full/ncomms9899.html
403 53BP1 and the LINC Complex Promote Microtubule-Dependent DSB Mobility and DNA Repair.
http://www.cell.com/cell/abstract/S0092-8674(15)01327-6
402 The nuclease of the CRISPR-Cas9 genomic editing system is highly effective at ignoring off-target sites.
http://www.sciencemag.org/content/350/6262/823.abstract
401 In Drosophila larvae, mutation of a single microRNA locus affects the animal’s ability to correct its orientation if turned upside down.
http://www.sciencemag.org/content/350/6262/815.abstract
400 Structural and biochemical basis for induced self-propagation of NLRC4.
http://www.sciencemag.org/content/350/6259/399.abstract
399 Arf1 and HIV-1 Nef play interconnected roles to remodel the inner AP-1 layer of the clathrin coat.
http://www.sciencemag.org/content/350/6259/aac5137.abstract
398 A protein for silencing transposons in the germline binds to and silences newly synthesized transposon RNA.
http://www.sciencemag.org/content/350/6258/339.abstract
397 Concise total synthesis of glucosepane.
http://www.sciencemag.org/content/350/6258/294.abstract
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