420 Genetic and environmental influences interact with age and sex in shaping the human methylome.
http://www.nature.com/ncomms/2016/160330/ncomms11115/full/ncomms11115.html
419 4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
http://www.nature.com/ncomms/2016/160407/ncomms11231/full/ncomms11231.html
418 Reading Out Single-Molecule Digital RNA and DNA Isothermal Amplification in Nanoliter Volumes with Unmodified Camera Phones.
http://pubs.acs.org/doi/abs/10.1021/acsnano.5b07338
417 Editing of mouse and human immunoglobulin genes by CRISPR-Cas9 system.
http://www.nature.com/ncomms/2016/160309/ncomms10934/full/ncomms10934.html
416 Direct CRISPR spacer acquisition from RNA by a natural reverse transcriptase–Cas1 fusion protein.
http://science.sciencemag.org/content/351/6276/aad4234
415 Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.
http://science.sciencemag.org/content/351/6275/867
414 RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency.
http://www.nature.com/ncomms/2016/160128/ncomms10548/full/ncomms10548.html
413 MicroRNA-276 promotes egg-hatching synchrony by up-regulating brm in locusts.
http://www.pnas.org/content/113/3/584.abstract
412 A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle.
http://science.sciencemag.org/content/351/6270/271
411 The regenerative properties of muscle stem cells decline with age as the stem cells enter an irreversible state of senescence; a study of mouse muscle stem cells reveals that entry into senescence is an autophagy-dependent process and promoting autophagy in old satellite cells can reverse senescence and restore their regenerative properties in an injury model.
http://www.nature.com/nature/journal/v529/n7584/full/nature16187.html
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