575 A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.
https://www.nature.com/articles/s41586-020-2477-4
574 CRISPR-CasΦ from huge phages is a hypercompact genome editor.
https://science.sciencemag.org/content/369/6501/333
573 Oncometabolites suppress DNA repair by disrupting local chromatin signalling.
https://www.nature.com/articles/s41586-020-2363-0
572 Very fast CRISPR on demand enables DNA repair studies at high resolution in space and time at specific genome locations.
https://science.sciencemag.org/content/368/6496/1265
571 Selective prebiotic formation of RNA pyrimidine and DNA purine nucleosides.
https://www.nature.com/articles/s41586-020-2330-9
570 Spatially regulated editing of genetic information within a neuron.
https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa172/5809668
569 An RNA polymerase ribozyme that synthesizes its own ancestor.
https://www.pnas.org/content/117/6/2906
568 Monosomes actively translate synaptic mRNAs in neuronal processes.
https://science.sciencemag.org/content/367/6477/eaay4991
567 A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases.
https://www.nature.com/articles/s41586-019-1786-y
566 Harnessing type I CRISPR–Cas systems for genome engineering in human cells.
https://www.nature.com/articles/s41587-019-0310-0
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