563 A CRISPR-mediated imaging approach, LiveFISH, enables real-time tracking of DNA and RNA in living cells.
https://science.sciencemag.org/content/365/6459/1301
562 A unified mechanism for intron and exon definition and back-splicing.
https://www.nature.com/articles/s41586-019-1523-6
561 Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly.
https://science.sciencemag.org/content/365/6456/922
560 CRISPR-associated nucleases are used to control multiscale properties of DNA-based materials.
https://science.sciencemag.org/content/365/6455/780
559 Drugging an undruggable pocket on KRAS.
https://www.pnas.org/content/116/32/15823
558 Rotation tracking of genome-processing enzymes using DNA origami rotors.
https://www.nature.com/articles/s41586-019-1397-7
557 Clockophagy is a novel selective autophagy process favoring ferroptosis.
https://advances.sciencemag.org/content/5/7/eaaw2238
556 Programmable cytidine-to-uridine RNA editing with an evolved ADAR2 fused to CRISPR-Cas13 expands the RNA editing toolbox.
https://science.sciencemag.org/content/365/6451/382
555 RNA-guided DNA insertion with CRISPR-associated transposases.
https://science.sciencemag.org/content/365/6448/48
554 Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins.
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(19)30249-5
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