1025 Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.
https://www.nature.com/articles/s41586-018-0806-7
1024 Impaired immune surveillance accelerates accumulation of senescent cells and aging.
https://www.nature.com/articles/s41467-018-07825-3#ref-CR67
1023 Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.
https://www.cell.com/cell/fulltext/S0092-8674(18)31333-3
1022 Anti-NKG2A mAb Is a Checkpoint Inhibitor that Promotes Anti-tumor Immunity by Unleashing Both T and NK Cells.
https://www.cell.com/cell/fulltext/S0092-8674(18)31322-9
1021 Protein kinase p38α signaling in dendritic cells regulates colon inflammation and tumorigenesis.
https://www.pnas.org/content/115/52/E12313
1020 Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.
https://www.pnas.org/content/115/52/13347
1019 MEK inhibition enhances oncolytic virus immunotherapy through increased tumor cell killing and T cell activation.
http://stm.sciencemag.org/content/10/471/eaau0417
1018 High-affinity allergen-specific human antibodies cloned from single IgE B cell transcriptomes.
http://science.sciencemag.org/content/362/6420/1306
1017 Trivalent RING Assembly on Retroviral Capsids Activates TRIM5 Ubiquitination and Innate Immune Signaling.
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(18)30545-6
1016 An integrated RNA-sequencing approach demonstrates that CXCL13+ TH1-like cells are preferentially enriched in microsatellite-instable tumours from patients with colorectal cancer, and IGFLR1 is identified as a co-stimulatory molecule.
https://www.nature.com/articles/s41586-018-0694-x
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