1320 Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
https://immunology.sciencemag.org/content/6/62/eabl4340
1319 Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
https://www.nature.com/articles/s41586-021-03791-x
1318 Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques.
https://www.nature.com/articles/s41586-021-03732-8
1317 Soluble mannose receptor induces proinflammatory macrophage activation and metaflammation.
https://www.pnas.org/content/118/31/e2103304118
1316 Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants.
https://www.nature.com/articles/s41586-021-03673-2
1315 Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma.
https://science.sciencemag.org/content/373/6553/eabf7844
1314 A resident stromal cell population actively restrains innate immune response in the propagation phase of colitis pathogenesis in mice.
https://stm.sciencemag.org/content/13/603/eabb5071
1313 BNT162b2 vaccine induces neutralizing antibodies and poly-specific T cells in humans.
https://www.nature.com/articles/s41586-021-03653-6
1312 Acetate—a major gut microbial metabolite—increases the production of IgA in the colon, alters the capacity of the IgA pool to bind to specific microorganisms and alters the localization of these bacteria within the colon.
https://www.nature.com/articles/s41586-021-03727-5
1311 Telomere dysfunction instigates inflammation in inflammatory bowel disease.
https://www.pnas.org/content/118/29/e2024853118
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