177 Simian adenoviruses screened from wild-derived candidates can prime T cell responses in man and may serve as new vaccine vector candidates.
http://stm.sciencemag.org/content/4/115/115ra2.abstract
176 An adenoviral HCV vaccine induces antiviral T cell responses in human volunteers.
http://stm.sciencemag.org/content/4/115/115ra1.abstract
175 Antibody-based protection against HIV infection by vectored immunoprophylaxis.
http://www.nature.com/nature/journal/v481/n7379/full/nature10660.html
174 Osteoarthritis, the breakdown of cartilage in synovial joints, has long been viewed as the result of 'wear and tear', but this report shows that dysregulation of the complement system has an active role in the pathogenesis of this disease.
http://www.nature.com/nm/journal/v17/n12/abs/nm.2543.html
173 Glycoconjugate vaccines—such as those targeting some bacteria—couple a glycan to a protein to provide T cell help to B cells and induce polysaccharide-specific IgGs. T cell help has been thought to be conferred by recognition of the protein portion by T cells. A glycan-peptide conjugate can induce T cells specific for the glycan moiety, which could help inform future glycoconjugate vaccine development.
http://www.nature.com/nm/journal/v17/n12/abs/nm.2535.html
172 Human monocytes are severely impaired in base and DNA double-strand break repair that renders them vulnerable to oxidative stress.
http://www.pnas.org/content/108/52/21105.abstract
171 Inhibition of calcium signaling is critical for the suppression of T cell responses by regulatory T cells.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;4/204/ra90
170 Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination.
http://jem.rupress.org/content/208/13/2733.abstract
169 A nonreplicating subunit vaccine protects mice against lethal Ebola virus challenge.
http://www.pnas.org/content/108/51/20695.abstract
168 Vaccination with M2e-Based Multiple Antigenic Peptides: Characterization of the B Cell Response and Protection Efficacy in Inbred and Outbred Mice.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0028445
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