282 Successful pregnancy requires immune tolerance against paternal antigens expressed by the fetus; here pregnancy is shown to stimulate the selective accumulation of maternal immune-suppressive regulatory T cells with fetal specificity that are retained post-partum, which may explain the protective benefits of prior pregnancy against pre-eclampsia and other complications in subsequent pregnancy.
http://www.nature.com/nature/journal/v490/n7418/full/nature11462.html
281 Structural and genetic basis for development of broadly neutralizing influenza antibodies.
http://www.nature.com/nature/journal/v489/n7417/full/nature11371.html
280 Three broadly neutralizing human monoclonal antibodies protect mice against influenza B.
http://www.sciencemag.org/content/337/6100/1343.abstract
279 Nonviral delivery of self-amplifying RNA vaccines.
http://www.pnas.org/content/109/36/14604.abstract
278 A vaccine directed to B cells and produced by cell-free protein synthesis generates potent antilymphoma immunity.
http://www.pnas.org/content/109/36/14526.abstract
277 A voltage-gated sodium channel is essential for the positive selection of CD4+ T cells.
http://www.nature.com/ni/journal/v13/n9/abs/ni.2379.html
276 T cells become licensed in the lung to enter the central nervous system.
http://www.nature.com/nature/journal/v488/n7413/full/nature11337.html
275 Lippmann et al. present a protocol for differentiating human pluripotent stem cells into blood-brain barrier endothelial cells. The cells should be useful for studying this endothelial barrier, including screening for drugs that can cross from the blood to the brain.
http://www.nature.com/nbt/journal/v30/n8/abs/nbt.2247.html
274 Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes.
http://www.cell.com/cell-host-microbe/abstract/S1931-3128(12)00232-6
273 Pathological crystallization of human immunoglobulins.
http://www.pnas.org/content/109/33/13359.abstract
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