452 Enzymes secreted by a bacterial pathogen turn immune responses against themselves.
http://www.sciencemag.org/content/342/6160/863.abstract
451 Immunosignatures can predict vaccine efficacy.
http://www.pnas.org/content/110/46/18614.abstract
450 The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2710.html
449 Intergenic long noncoding RNAs (lincRNAs) regulate gene expression in various tissues. Zhao and colleagues identify 1,524 lincRNA clusters in thymocytes and mature T cell subsets and reveal dynamic and cell-specific patterns of lincRNA expression during T cell differentiation.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2712.html
448 Effector responses of NK cells occur via cytoxicity and cytokine secretion. Malarkannan and colleagues identify a signaling module that selectively controls the cytokine production of NK cells.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2708.html
447 High-throughput identification of antigen-specific TCRs by TCR gene capture.
http://www.nature.com/nm/journal/v19/n11/abs/nm.3359.html
446 Diurnal regulation of an immune cell lineage in the intestine protects against inflammatory disease in mice.
http://www.sciencemag.org/content/342/6159/727.abstract
445 The duration of T cell receptor contact with antigen modulates the pattern of downstream signaling to determine CD4+ T cell fate.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/300/ra97
444 Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma.
http://www.nature.com/nature/journal/v503/n7474/full/nature12614.html
443 Vaccines based on structure-based design provide protection against infectious diseases. (Review).
http://www.expert-reviews.com/doi/abs/10.1586/14760584.2013.840092
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