248 Chloride concentrations inside subcellular organelles of living cells can now be measured in a pH-independent manner using a DNA nanodevice, offering a tool for studying chloride homeostasis and its associated diseases.
http://www.nature.com/nnano/journal/v10/n7/abs/nnano.2015.130.html
247 Eye-like ocelloids are built from different endosymbiotically acquired components.
http://www.nature.com/nature/journal/v523/n7559/full/nature14593.html
246 Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice.
http://www.nature.com/ncomms/2015/150624/ncomms8450/full/ncomms8450.html
245 Cell death during crisis is mediated by mitotic telomere deprotection.
http://www.nature.com/nature/journal/v522/n7557/full/nature14513.html
244 A high percentage of smooth muscle cells in atherosclerotic lesions lose expression of smooth muscle marker proteins and acquire the phenotype of other cell types, a process of functional importance in lesion pathogenesis that is controlled by the transcription factor KLF4.
http://www.nature.com/nm/journal/v21/n6/abs/nm.3866.html
243 The miR-200 family of miRNAs is upregulated in diabetes and leads to the apoptosis of pancreatic beta cells, while its knockout prevents this pathology.
http://www.nature.com/nm/journal/v21/n6/abs/nm.3862.html
242 An “organelle knockout” strategy reveals that cancer cells but not normal cells can divide in the absence of centrosomes.
http://www.sciencemag.org/content/348/6239/1155.abstract
241 The lymphatic endothelium is thought to arise entirely from trans-differentiation of the venous endothelium; a new mechanism of lymphatic vessel formation is identified in zebrafish, whereby the lymphatic vessels derive from specialized angioblasts within the floor of the cardinal vein.
http://www.nature.com/nature/journal/v522/n7554/full/nature14425.html
240 Systematic humanization of yeast genes reveals conserved functions and genetic modularity.
http://www.sciencemag.org/content/348/6237/921
239 Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro.
http://www.pnas.org/content/112/20/E2725
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