498 Single-cell and single-nucleus RNA sequencing are used to construct a cellular atlas of the human heart that will aid further research into cardiac physiology and disease.
https://www.nature.com/articles/s41586-020-2797-4
497 Gene expression is examined at the single-cell level during early human development.
https://science.sciencemag.org/content/370/6518/eaba7721
496 Down-regulation of Beclin1 promotes direct cardiac reprogramming.
https://stm.sciencemag.org/content/12/566/eaay7856
495 O-glycan–rich mucus secretion segregates colon microbiota from host cells to prevent inflammation during fecal elimination.
https://science.sciencemag.org/content/370/6515/467
494 An organoid-based screening platform maps the genetic interactions underlying intestinal development and regeneration, showing that retinoic acid metabolism maintains the balance between regeneration and homeostasis, and that an antagonist of the retinoid X receptor promotes regeneration in vivo.
https://www.nature.com/articles/s41586-020-2776-9
493 Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling.
https://www.pnas.org/content/117/38/23617
492 The Human and Mouse Enteric Nervous System at Single-Cell Resolution.
https://www.cell.com/cell/fulltext/S0092-8674(20)30994-6
491 Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution.
https://www.cell.com/cell/fulltext/S0092-8674(20)31004-7
490 A single-cell transcriptomic atlas characterizes ageing tissues in the mouse.
https://www.nature.com/articles/s41586-020-2496-1
489 Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.
https://www.pnas.org/content/117/27/15818
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