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Cancer Biology

Cancer Biology

 
117 A tumour suppressor network relying on the polyamine–hypusine axis.
http://www.nature.com/nature/journal/v487/n7406/full/nature11126.html

116 Rac1b mediates the matrix metalloproteinase–induced epithelial-mesenchymal transition in lung adenocarcinoma and is a potential therapeutic target in early-stage lung cancer.
http://stm.sciencemag.org/content/4/142/142ra95.abstract

115 A compendium of SRM assays for cancer-associated proteins provides a resource for accelerating and planning biomarker verification studies.
http://stm.sciencemag.org/content/4/142/142ra94.abstract

114 Quantitative Imaging of Epithelial Cell Scattering Identifies Specific Inhibitors of Cell Motility and Cell-Cell Dissociation.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/231/rs5

113 A hybrid microfluidic/semiconductor chip analyzes single, immunomagnetically tagged ovarian cancer cells in unprocessed biological samples.
http://stm.sciencemag.org/content/4/141/141ra92.abstract

112 ALK inhibitors induce complete tumor regression in a mouse model of ALK-driven neuroblastoma.
http://stm.sciencemag.org/content/4/141/141ra91.abstract

111 Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential.
http://www.sciencemag.org/content/337/6090/104.abstract

110 Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.
http://www.nature.com/nature/journal/v486/n7404/full/nature11156.html

109 Electron transfer-based combination therapy of cisplatin with tetramethyl-p-phenylenediamine for ovarian, cervical, and lung cancers.
http://www.pnas.org/content/109/26/10175.abstract

108 mTOR Inhibitors Synergize on Regression, Reversal of Gene Expression, and Autophagy in Hepatocellular Carcinoma.
http://stm.sciencemag.org/content/4/139/139ra84.abstract

107 Catalytic DNA molecules that target the transcription factor c-jun inhibit skin cancer growth in mice.
http://stm.sciencemag.org/content/4/139/139ra82.abstract

106 The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.
http://www.nature.com/nature/journal/v486/n7403/full/nature10983.html

105 Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells.
http://www.cell.com/abstract/S0092-8674(12)00571-5

104 Implanted adipose progenitor cells as physicochemical regulators of breast cancer.
http://www.pnas.org/content/109/25/9786

103 Identifying Gene Pathways Associated with Cancer Characteristics via Sparse Statistical Methods.
http://www.computer.org/csdl/trans/tb/2012/04/ttb2012040966-abs.html

102 A Sparse Regulatory Network of Copy-Number Driven Gene Expression Reveals Putative Breast Cancer Oncogenes.
http://www.computer.org/csdl/trans/tb/2012/04/ttb2012040947-abs.html

101 Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes.
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002511

100 Functional genomics identifies therapeutic targets for MYC-driven cancer.
http://www.pnas.org/content/109/24/9545.abstract

99 The binding of angiopoietin-like proteins to immune-inhibitory receptors maintains ‘stemness’ of haematopoietic stem cells and supports leukaemia development.
http://www.nature.com/nature/journal/v485/n7400/full/nature11095.html

98 Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer.
http://www.pnas.org/content/109/22/8699.abstract

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