157 PDK1 in the nucleus drives oncogenesis in mice and correlates with human prostate tumor grade.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/249/ra80
156 In Vitro and In Vivo Near-Infrared Photothermal Therapy of Cancer Using Polypyrrole Organic Nanoparticles.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201202625/abstract
155 A cell-penetrating lupus anti-DNA antibody inhibits DNA repair, sensitizes cancer cells to DNA-damaging therapy in vitro and in vivo, and is synthetically lethal to BRCA2-deficient human cancer cells.
http://stm.sciencemag.org/content/4/157/157ra142.abstract
154 In a Drosophila imaginal epithelial disc system, mutations that lead to mitochondrial dysfunction can also promote tumorigenic growth of neighbouring cells expressing an activated Ras oncogene.
http://www.nature.com/nature/journal/v490/n7421/full/nature11452.html
153 Minnelide prevents tumor formation, causes tumor regression, and increases survival in multiple models of pancreatic cancer.
http://stm.sciencemag.org/content/4/156/156ra139.abstract
152 Tumor genome sequencing reveals the molecular basis of a patient’s unexpected and dramatic response to a cancer drug.
http://www.sciencemag.org/content/338/6104/221.abstract
151 Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
http://www.pnas.org/content/109/40/16348.abstract
150 The Design of a Heterocellular 3D Architecture and its Application to Monitoring the Behavior of Cancer Cells in Response to the Spatial Distribution of Endothelial Cells.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201200687/abstract
149 Comprehensive molecular portraits of human breast tumours.
http://www.nature.com/nature/journal/v490/n7418/full/nature11412.html
148 Two Vav isoforms could be targeted to prevent breast tumors from metastasizing to the lung.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;5/244/ra71
147 Comprehensive genomic characterization of squamous cell lung cancers.
http://www.nature.com/nature/journal/v489/n7417/full/nature11404.html
146 Molecular mechanism of pancreatic tumor metastasis inhibition by Gd@C82(OH)22 and its implication for de novo design of nanomedicine.
http://www.pnas.org/content/109/38/15431.abstract
145 Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer.
http://www.pnas.org/content/109/38/15312.abstract
144 The deubiquitinating enzyme BAP1 is implicated in myelodysplastic syndrome.
http://www.sciencemag.org/content/337/6101/1541.abstract
143 Tumour lineage-homing cell-penetrating peptides as anticancer molecular delivery systems.
http://www.nature.com/ncomms/journal/v3/n7/full/ncomms1952.html
142 High-fat or ethinyl-oestradiol intake during pregnancy increases mammary cancer risk in several generations of offspring.
http://www.nature.com/ncomms/journal/v3/n9/full/ncomms2058.html
141 A fusion gene detected in a small subset of human brain tumors encodes a potentially druggable target.
http://www.sciencemag.org/content/337/6099/1231.abstract
140 Near-Infrared Fluorescent Silica/Porphyrin Hybrid Nanorings for In Vivo Cancer Imaging.
http://onlinelibrary.wiley.com/doi/10.1002/adfm.201200219/abstract
139 Gene-Targeting of Phd2 Improves Tumor Response to Chemotherapy and Prevents Side-Toxicity.
http://www.cell.com/cancer-cell/abstract/S1535-6108(12)00289-9
138 The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites.
http://www.cell.com/abstract/S0092-8674(12)00872-0
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