237 ROS Production and NF-B Activation Triggered by RAC1 Facilitate WNT-Driven Intestinal Stem Cell Proliferation and Colorectal Cancer Initiation.
http://www.cell.com/cell-stem-cell/abstract/S1934-5909(13)00142-2
236 Placenta-derived gp96 as a multivalent prophylactic cancer vaccine.
http://www.nature.com/srep/2013/130606/srep01947/full/srep01947.html
235 A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence.
http://www.nature.com/nature/journal/v498/n7452/full/nature12154.html
234 Control of angiogenesis by AIBP-mediated cholesterol efflux.
http://www.nature.com/nature/journal/v498/n7452/full/nature12166.html
233 A protein complex identified as a negative regulator of the mTORC1 protein kinase complex has tumor suppressor functions.
http://www.sciencemag.org/content/340/6136/1100.abstract
232 Inhibition of adenosine receptors could reduce metastasis by enhancing prenylation-dependent signaling that promotes cell-cell adhesion.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/277/ra39
231 Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling.
http://www.nature.com/nature/journal/v497/n7451/full/nature12205.html
230 Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model.
http://jem.rupress.org/content/210/5/917.abstract
229 Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo.
http://www.pnas.org/content/110/22/9025.abstract
228 The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation.
http://www.cell.com/abstract/S0092-8674(13)00532-1
227 Nontoxic radioactive Listeria is a highly effective therapy against metastatic pancreatic cancer.
http://www.pnas.org/content/110/21/8668
226 MicroRNA profiling of 1,302 human breast tumour samples provides an overview of the miRNA landscape and its regulation, revealing context-dependent interactions, broad prognostic value of miRNA signatures and an important modulatory role for miRNAs in the biology of breast tumours devoid of copy-number aberrations.
http://www.nature.com/nature/journal/v497/n7449/full/nature12108.html
225 The oncolytic and immunotherapeutic vaccinia virus Pexa-Vec (JX-594) induces antibody-mediated complement-dependent cancer cell cytolysis in rabbits and cancer patients, prolonging their survival.
http://stm.sciencemag.org/content/5/185/185ra63.abstract
224 Mutations of histones in some cancers result in inhibition of enzymes that lay down epigenetic marks on chromatin.
http://www.sciencemag.org/content/340/6134/857.abstract
223 Cyclophosphamide Triggers Follicle Activation and “Burnout”; AS101 Prevents Follicle Loss and Preserves Fertility.
http://stm.sciencemag.org/content/5/185/185ra62.abstract
222 In silico discovery of small-molecule Ras inhibitors that display antitumor activity by blocking the Ras–effector interaction.
http://www.pnas.org/content/110/20/8182.abstract
221 Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist.
http://www.pnas.org/content/110/20/E1857.abstract
220 Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth.
http://www.pnas.org/content/110/20/8170.abstract
219 A Novel Fully Automated Molecular Diagnostic System (AMDS) for Colorectal Cancer Mutation Detection.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062989
218 Gene network reconstruction reveals cell cycle and antiviral genes as major drivers of cervical cancer.
http://www.nature.com/ncomms/journal/v4/n5/full/ncomms2693.html
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