345 Mutant KRAS is a druggable target for pancreatic cancer.
http://www.pnas.org/content/110/51/20723.abstract
344 CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis.
http://www.pnas.org/content/110/51/20717.abstract
343 Ascites analysis by a microfluidic chip allows tumor-cell profiling.
http://www.pnas.org/content/110/51/E4978.abstract
342 p53 status determines the role of autophagy in pancreatic tumour development.
http://www.nature.com/nature/journal/v504/n7479/full/nature12865.html
341 Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
http://www.nature.com/nchembio/journal/v9/n12/abs/nchembio.1367.html
340 Preventing the methylation of VEGFR-2 could attenuate pathological angiogenesis in cancer.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/304/ra104
339 Targeting signaling pathways upstream of oncogenic Ras may have therapeutic benefit in the treatment of leukemia.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;6/304/ra105
338 A melanocyte lineage program confers resistance to MAP kinase pathway inhibition.
http://www.nature.com/nature/journal/v504/n7478/full/nature12688.html
337 The activity of a specific metabolite of cholesterol may help explain why obesity is a risk factor for breast cancer.
http://www.sciencemag.org/content/342/6162/1094.abstract
336 Bioavailable copper modulates oxidative phosphorylation and growth of tumors.
http://www.pnas.org/content/110/48/19507.abstract
335 The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide.
http://www.sciencemag.org/content/342/6161/971.abstract
334 Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment.
http://www.sciencemag.org/content/342/6161/967.abstract
333 Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression.
http://www.pnas.org/content/110/47/18940.abstract
332 Photoswitchable nanoparticles for in vivo cancer chemotherapy.
http://www.pnas.org/content/110/47/19048.abstract
331 miRNA and mRNA cancer signatures determined by analysis of expression levels in large cohorts of patients.
http://www.pnas.org/content/110/47/19160.abstract
330 mTOR plays critical roles in pancreatic cancer stem cells through specific and stemness-related functions.
http://www.nature.com/srep/2013/131115/srep03230/full/srep03230.html
329 DIM (3,3′-diindolylmethane) confers protection against ionizing radiation by a unique mechanism.
http://www.pnas.org/content/110/46/18650.abstract
328 Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug.
http://www.pnas.org/content/110/46/18638.abstract
327 Combining two strategies to improve perfusion and drug delivery in solid tumors.
http://www.pnas.org/content/110/46/18632.abstract
326 Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.
http://www.ncbi.nlm.nih.gov/pubmed/23396970
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