457 Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration.
http://stke.sciencemag.org/content/7/345/ra92.abstract
456 The growth of tumours is supported by tumour production of lactic acid, which polarizes tumour-associated macrophages to an M2 phenotype through a pathway dependent on hypoxia-inducible factor 1α.
http://www.nature.com/nature/journal/v513/n7519/full/nature13490.html
455 Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes.
http://www.pnas.org/content/111/38/13948.abstract
454 Small-molecule Bax agonists for cancer therapy.
http://www.nature.com/ncomms/2014/140917/ncomms5935/full/ncomms5935.html
453 A regulator of the enzyme that makes the building blocks of DNA provides a new target for anticancer drugs.
http://www.sciencemag.org/content/345/6203/1512.abstract
452 Fructose-1,6-bisphosphatase opposes renal carcinoma progression.
http://www.nature.com/nature/journal/v513/n7517/full/nature13557.html
451 Comprehensive molecular characterization of gastric adenocarcinoma.
http://www.nature.com/nature/journal/v513/n7517/full/nature13480.html
450 Asymmetric triplex metallohelices with high and selective activity against cancer cells.
http://www.nature.com/nchem/journal/v6/n9/abs/nchem.2024.html
449 The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.
http://www.pnas.org/content/111/35/E3689.abstract
448 The translation of many messenger RNAs that encode important oncogenes and transcription factors depends on the eIF4A RNA helicase to resolve G-quadruplex structures, implying eIF4A inhibition as an effective cancer therapy.
http://www.nature.com/nature/journal/v513/n7516/full/nature13485.html
447 Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.
http://www.nature.com/nature/journal/v513/n7516/full/nature13528.html
446 Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality.
http://www.cell.com/cell/abstract/S0092-8674(14)00977-5
445 Small RNA combination therapy for lung cancer.
http://www.pnas.org/content/111/34/E3553.abstract
444 A vaccine targeting mutant IDH1 induces antitumour immunity.
http://www.nature.com/nature/journal/v512/n7514/full/nature13387.html
443 Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
http://www.nature.com/nature/journal/v512/n7513/full/nature13600.html
442 miRNA-128 Suppresses Prostate Cancer by Inhibiting BMI-1 to Inhibit Tumor-Initiating Cells.
http://cancerres.aacrjournals.org/content/74/15/4183.abstract
441 DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy.
http://pubs.acs.org/doi/abs/10.1021/nn502058j
440 DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis.
http://www.nature.com/ncb/journal/v16/n8/abs/ncb3010.html
439 Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.
http://www.nature.com/ncb/journal/v16/n8/abs/ncb2994.html
438 Tumor genomes are peppered with mobile repeat sequences that carry along adjacent DNA when they insert into new genomic sites.
http://www.sciencemag.org/content/345/6196/1251343.abstract
|
