505 IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies.
http://stm.sciencemag.org/content/7/272/272ra12
504 Comprehensive genomic characterization of head and neck squamous cell carcinomas.
http://www.nature.com/nature/journal/v517/n7536/full/nature14129.html
503 ADAM8 as a drug target in pancreatic cancer.
http://www.nature.com/ncomms/2015/150127/ncomms7175/full/ncomms7175.html
502 Examination of HER3 targeting in cancer using monoclonal antibodies.
http://www.pnas.org/content/112/3/839.abstract
501 mTORC1-mediated translational elongation limits intestinal tumour initiation and growth.
http://www.nature.com/nature/journal/v517/n7535/full/nature13896.html
500 Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.
http://stm.sciencemag.org/content/7/271/271ra7
499 Interfering with stem cell-specific gatekeeper functions controls tumour initiation and malignant progression of skin tumours.
http://www.nature.com/ncomms/2015/150122/ncomms6874/full/ncomms6874.html
498 Efficient Delivery of Therapeutic miRNA Nanocapsules for Tumor Suppression.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201403387/abstract
497 A potential therapeutic strategy is identified for tumor cells that maintain their telomeres by an unusual mechanism.
http://www.sciencemag.org/content/347/6219/273.abstract
496 Biopolymer implants enhance the efficacy of adoptive T-cell therapy.
http://www.nature.com/nbt/journal/v33/n1/abs/nbt.3104.html
495 Innate sensing of microbial products promotes wound-induced skin cancer.
http://www.nature.com/ncomms/2015/150109/ncomms6932/full/ncomms6932.html
494 BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells.
http://www.nature.com/ncomms/2015/150109/ncomms6987/full/ncomms6987.html
493 Only three driver gene mutations are required for the development of lung and colorectal cancers.
http://www.pnas.org/content/112/1/118.abstract
492 Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors.
http://www.pnas.org/content/111/52/18637.abstract
491 In vivo anticancer activity of rhomboidal Pt(II) metallacycles.
http://www.pnas.org/content/111/52/18448.abstract
490 Using transplantation and lineage-tracing strategies, protein C receptor is identified as a marker of mammary stem cells in mice, with potential implications for understanding the initiation of breast cancer.
http://www.nature.com/nature/journal/v517/n7532/full/nature13851.html
489 Variation in cancer risk among tissues can be explained by the number of stem cell divisions.
http://www.sciencemag.org/content/347/6217/78.abstract
488 Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth.
http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00456-5
487 A BCL6/BCOR/SIRT1 Complex Triggers Neurogenesis and Suppresses Medulloblastoma by Repressing Sonic Hedgehog Signaling.
http://www.cell.com/cancer-cell/abstract/S1535-6108(14)00451-6
486 Acetate Dependence of Tumors.
http://www.cell.com/cell/abstract/S0092-8674(14)01451-2
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