545 Marrow-infiltrating lymphocytes (MILs) may be used as adoptive cell therapy for multiple myeloma.
http://stm.sciencemag.org/content/7/288/288ra78.abstract
544 Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia.
http://www.nature.com/ni/journal/vaop/ncurrent/full/ni.3160.html
543 A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.
http://www.sciencemag.org/content/348/6236/803.abstract
542 Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing.
http://www.nature.com/ncomms/2015/150514/ncomms8103/full/ncomms8103.html
541 Noninvasive imaging of immune responses.
http://www.pnas.org/content/112/19/6146
540 SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents.
http://www.cell.com/cell-metabolism/abstract/S1550-4131(15)00164-3
539 ITIM-containing receptor LAIR1 supports self-renewal and survival of acute myeloid leukaemia stem cells through a signalling pathway that includes the SHP-1 phosphatase, CAMK1 kinase and CREB transcription factor.
http://www.nature.com/ncb/journal/v17/n5/abs/ncb3158.html
538 Two susceptibility loci identified for prostate cancer aggressiveness.
http://www.nature.com/ncomms/2015/150420/ncomms7889/full/ncomms7889.html
537 Sequential cancer mutations in cultured human intestinal stem cells.
http://www.nature.com/nature/journal/v521/n7550/full/nature14415.html
536 Mutant MHC class II epitopes drive therapeutic immune responses to cancer.
http://www.nature.com/nature/journal/v520/n7549/full/nature14426.html
535 Monoclonal antibodies against GARP/TGF-β1 complexes inhibit the immunosuppressive activity of human regulatory T cells in vivo.
http://stm.sciencemag.org/content/7/284/284ra56
534 A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis.
http://www.nature.com/nature/journal/v520/n7547/full/nature14403.html
533 Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.
http://www.nature.com/nature/journal/v520/n7547/full/nature14292.html
532 Postsurgical adjuvant or metastatic renal cell carcinoma therapy models reveal potent antitumor activity of metronomic oral topotecan with pazopanib.
http://stm.sciencemag.org/content/7/282/282ra50
531 A humanized mouse model facilitates the identification of T cell receptors for unmutated cancer antigens.
http://www.nature.com/nbt/journal/v33/n4/abs/nbt.3147.html
530 Soluble proteins shed by tumors stimulate natural killer cell–mediated antitumor immunity in mice.
http://www.sciencemag.org/content/348/6230/136.abstract
529 An anticancer drug is more effective against tumors that carry more mutations.
http://www.sciencemag.org/content/348/6230/124.abstract
528 Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.
http://www.pnas.org/content/112/13/4086.abstract
527 The nuclear translocation of ERK1/2 as an anticancer target.
http://www.nature.com/ncomms/2015/150330/ncomms7685/full/ncomms7685.html
526 Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design.
http://www.nature.com/ncomms/2015/150320/ncomms7582/full/ncomms7582.html
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