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Cancer Biology

Cancer Biology

 
605 Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.
http://stm.sciencemag.org/content/7/315/315ra188

604 Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy.
http://www.sciencemag.org/content/350/6264/1084.abstract

603 Gut microbes modulate the effectiveness of cancer immunotherapies in mice.
http://www.sciencemag.org/content/350/6264/1079.abstract

602 An immune cell subset called patrolling monocytes prevents tumor lung metastasis in mice.
http://www.sciencemag.org/content/350/6263/985.abstract

601 Formyl peptide receptor 1 helps the immune system sense dying tumor cells.
http://www.sciencemag.org/content/350/6263/972.abstract

600 Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.
http://stm.sciencemag.org/content/7/314/314ra186

599 ASS1, a urea cycle enzyme, promotes cancer cell proliferation by facilitating pyrimidine synthesis via CAD (carbamoyl-phosphate synthase 2, aspartate transcarbamylase, and dihydroorotase complex) activation.
http://www.nature.com/nature/journal/v527/n7578/full/nature15529.html

598 MicroRNA–mRNA interactions underlying colorectal cancer molecular subtypes.
http://www.nature.com/ncomms/2015/151117/ncomms9878/full/ncomms9878.html

597 Antibody-Modified Reduced Graphene Oxide Films with Extreme Sensitivity to Circulating Tumor Cells.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201502615/full

596 Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma.
http://www.nature.com/ncomms/2015/151110/ncomms9839/full/ncomms9839.html

595 Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy.
http://www.nature.com/nature/journal/v527/n7577/full/nature15520.html

594 Oxidative stress inhibits distant metastasis by human melanoma cells.
http://www.nature.com/nature/journal/v527/n7577/full/nature15726.html

593 Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.
http://stm.sciencemag.org/content/7/312/312ra176

592 Cancer and the gut microbiota: An unexpected link.
http://stm.sciencemag.org/content/7/271/271ps1.full

591 Malignant Transformation of Hymenolepis nana in a Human Host.
http://www.nejm.org/doi/full/10.1056/NEJMoa1505892?query=featured_home

590 RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics.
http://www.cell.com/cancer-cell/abstract/S1535-6108(15)00349-9

589 Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein.
http://www.cell.com/cancer-cell/abstract/S1535-6108(15)00334-7

588 Oncogenes encoded by DNA tumor viruses subvert antiviral immunity.
http://www.sciencemag.org/content/350/6260/568.abstract

587 Alternative transcription initiation leads to expression of a novel ALK isoform in cancer.
http://www.nature.com/nature/journal/v526/n7573/full/nature15258.html

586 Identification of an oncogenic RAB protein.
http://www.sciencemag.org/content/350/6257/211.abstract

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