865 Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.
https://www.nature.com/articles/nature25795
864 The Cdx2 homeobox gene suppresses intestinal tumorigenesis through non–cell-autonomous mechanisms.
http://jem.rupress.org/content/215/3/911
863 Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity.
http://jem.rupress.org/content/215/3/877
862 A commensal strain of Staphylococcus epidermidis protects against skin neoplasia.
http://advances.sciencemag.org/content/4/2/eaao4502
861 Patient-derived organoids model treatment response of metastatic gastrointestinal cancers.
http://science.sciencemag.org/content/359/6378/920
860 Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence.
http://www.pnas.org/content/115/8/1801
859 Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy.
http://stm.sciencemag.org/content/10/428/eaaf7444
858 Renal cell cancers with mutations in a specific chromatin regulator have a better clinical response to immunotherapy.
http://science.sciencemag.org/content/359/6377/801
857 Inactivation of a chromatin remodeling complex in tumor cells enhances their sensitivity to killing by T cells.
http://science.sciencemag.org/content/359/6377/770
856 Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.
https://www.nature.com/articles/nm.4470
855 Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
https://www.nature.com/articles/nm.4464
854 A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
https://www.nature.com/articles/nm.4474
853 Targeting IRF3 as a YAP agonist therapy against gastric cancer.
http://jem.rupress.org/content/215/2/699
852 Asparagine bioavailability governs metastasis in a model of breast cancer.
https://www.nature.com/articles/nature25465
851 Targeting of p53- and PUMA-dependent apoptosis protects intestinal stem cells, but not cancer cells, against chemotherapy.
http://stm.sciencemag.org/content/10/427/eaam7610
850 HER kinase inhibition in patients with HER2- and HER3-mutant cancers.
https://www.nature.com/articles/nature25475
849 Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria.
http://science.sciencemag.org/content/359/6375/592
848 Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.
http://science.sciencemag.org/content/359/6375/582
847 Eradication of spontaneous malignancy by local immunotherapy.
http://stm.sciencemag.org/content/10/426/eaan4488
846 Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer.
http://www.pnas.org/content/115/5/1057
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