1134 Germline mutations in the Elongator complex gene ELP1 predispose individuals to the development of childhood medulloblastoma.
https://www.nature.com/articles/s41586-020-2164-5
1133 Integrating genomic features for non-invasive early lung cancer detection.
https://www.nature.com/articles/s41586-020-2140-0
1132 IL-6 blockade reverses bone marrow failure induced by human acute myeloid leukemia.
https://stm.sciencemag.org/content/12/538/eaax5104
1131 Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling.
https://stm.sciencemag.org/content/12/537/eaaw0262
1130 Control of brain tumor growth by reactivating myeloid cells with niacin.
https://stm.sciencemag.org/content/12/537/eaay9924
1129 Cysteine depletion induces pancreatic tumor ferroptosis in mice.
https://science.sciencemag.org/content/368/6486/85
1128 Microbiome analyses of blood and tissues suggest cancer diagnostic approach.
https://www.nature.com/articles/s41586-020-2095-1
1127 Inhibiting a specific isoform of TGFβ augments the effectiveness of checkpoint blockade therapy in cancer treatment.
https://stm.sciencemag.org/content/12/536/eaay8456
1126 Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis.
https://science.sciencemag.org/content/367/6485/1468
1125 SOX4-mediated repression of specific tRNAs inhibits proliferation of human glioblastoma cells.
https://www.pnas.org/content/117/11/5782
1124 Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
https://www.pnas.org/content/117/11/6047
1123 Peripheral T cell expansion predicts tumour infiltration and clinical response.
https://www.nature.com/articles/s41586-020-2056-8
1122 Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
https://www.nature.com/articles/s41586-020-2054-x
1121 Functional analysis of rare mutations in head and neck cancers reveals that NOTCH signaling is disrupted in most tumors.
https://science.sciencemag.org/content/367/6483/1264
1120 Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma.
https://stm.sciencemag.org/content/12/533/eaaw2672
1119 Vitamin C promotes anticancer adaptive immunity and enhances efficacy of immune checkpoint therapy.
https://stm.sciencemag.org/content/12/532/eaay8707
1118 CRISPR-engineered T cells in patients with refractory cancer.
https://science.sciencemag.org/content/367/6481/eaba7365
1117 A single-cell, spatially resolved analysis of breast cancer demonstrates the heterogeneity of tumour and stroma tissue and provides a more-detailed method of patient classification than the current histology-based system.
https://www.nature.com/articles/s41586-019-1876-x
1116 Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
https://www.nature.com/articles/s41586-020-2054-x
1115 Proteogenomic analyses of prospectively collected endometrial carcinomas provide insights into the role of underlying molecular pathways and the immune landscape that drive disease.
https://www.cell.com/cell/fulltext/S0092-8674(20)30107-0
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