274 Genetically engineered mice are an important aspect of human disease research. Here, the authors use artificial transcription activator-like effector-nucleases to generate a mouse line with a conditionally targeted allele and suggest that this method can be easily adapted to any gene in the mouse genome.
http://www.nature.com/ncomms/2014/140113/ncomms4045/full/ncomms4045.html
273 Biologically derived melanin electrodes in aqueous sodium-ion energy storage devices.
http://www.pnas.org/content/110/52/20912.abstract
272 Fluorescence in situ hybridization allows for next-generation sequencing of a large, difficult genome.
https://www.sciencemag.org/content/342/6165/1516.abstract
271 Synthesis and delivery of short, noncoding RNA by B lymphocytes.
http://www.pnas.org/content/110/50/20182.abstract
270 A Simple and Versatile Method for the Formation of Arrays of Giant Vesicles with Controlled Size and Composition.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201303290/abstract
269 Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells.
http://www.nature.com/nbt/journal/v31/n12/abs/nbt.2720.html
268 Development of a Sperm-Flagella Driven Micro-Bio-Robot.
http://onlinelibrary.wiley.com/doi/10.1002/adma.201302544/abstract
267 RNA-sequencing from single nuclei.
http://www.pnas.org/content/110/49/19802.abstract
266 An aptamer-based biosensor continuously measures the concentration of drug molecules in the blood of living animals and in patient samples.
http://stm.sciencemag.org/content/5/213/213ra165.abstract
265 Antibody biomarker discovery through in vitro directed evolution of consensus recognition epitopes.
http://www.pnas.org/content/110/48/19330.abstract
|
