23 A screen identifies a drug that specifically kills glycolysis-dependent cancer cells by inhibiting glucose uptake. Chan DA. (2011). Sci Transl Med 3:p. 94ra70
http://stm.sciencemag.org/content/3/94/94ra70.abstract
22 Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation. Sievers SA. et al. (2011). Nature 475:96-100.
http://www.nature.com/nature/journal/v475/n7354/full/nature10154.html
21 Ablation of a gene controlling fat breakdown can protect mice from cancer-associated uncontrolled loss of fat and muscle. Das SK. et al. (2011). Science 333: 233-238.
http://www.sciencemag.org/content/333/6039/233.abstract
20 MicroRNAs 103 and 107 regulate insulin sensitivity. Trajkovsky M. et al. (2011). Nature 474:649-653.
http://www.nature.com/nature/journal/v474/n7353/full/nature10112.html
19 A Key Enzyme in the Biogenesis of Lysosomes Is a Protease That Regulates Cholesterol Metabolism. Marschner K. et al. (2011). Science 333:87-90.
http://www.sciencemag.org/content/333/6038/87.abstract
18 N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Lucanic M. et al. (2011). Nature 473: 226-229.
http://www.nature.com/nature/journal/v473/n7346/full/nature10007.html
17 Anchored clathrate waters bind antifreeze proteins to ice. Garnham CP. et al. (2011). PNAS 108:7363-7367.
http://www.pnas.org/content/108/18/7363
16 Metabolite profiles and the risk of developing diabetes. Five branched-chain and aromatic amino acids had highly significant associations with future diabetes: isoleucine, leucine, valine, tyrosine and phenylalanine. Wang TJ et al. (2011). Nature Medicine 17:448–453.
http://www.nature.com/nm/journal/v17/n4/abs/nm.2307.html
15 Diatoms respire nitrate to survive dark and anoxic conditions. Kamp A. et al. (2011). PNAS 108:5649-5654.
http://www.pnas.org/content/108/14/5649.abstract
14 A functional RNA has been synthesized by an RNA enzyme from mononucleotide building blocks. Wochner A. et al. (2011). Science 332:209-212.
http://www.sciencemag.org/content/332/6026/209.abstract
|
