981 HRI kinase represses expression of fetal hemoglobin and provides a potential target for sickle cell disease treatment.
http://science.sciencemag.org/content/361/6399/285
980 Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo.
http://stm.sciencemag.org/content/10/450/eaam7710
979 Treating elderly subjects with two low-dose mTOR inhibitors that selectively block TORC1 led to a decrease in infection rates.
http://stm.sciencemag.org/content/10/449/eaaq1564
978 Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota.
https://www.nature.com/articles/s41590-018-0134-y
977 Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.
https://www.nature.com/articles/s41590-018-0132-0
976 Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity.
http://science.sciencemag.org/content/361/6397/57
975 Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4+ T Cells.
https://www.cell.com/immunity/fulltext/S1074-7613(18)30141-9
974 A direct link between MITF, innate immunity, and hair graying.
http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2003648
973 A live vaccine rapidly protects against cholera in an infant rabbit model.
http://stm.sciencemag.org/content/10/445/eaap8423
972 Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells.
https://www.nature.com/articles/s41586-018-0178-z
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