1181 Neutralization of IL-1α ameliorates Crohn’s disease-like ileitis by functional alterations of the gut microbiome.
https://www.pnas.org/content/116/52/26717
1180 High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.
https://www.cell.com/cell/fulltext/S0092-8674(19)31224-3
1179 Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia.
https://advances.sciencemag.org/content/5/12/eaax7331
1178 NS1 DNA vaccination protects against Zika infection through T cell–mediated immunity in immunocompetent mice.
https://advances.sciencemag.org/content/5/12/eaax2388
1177 Clec10a on skin macrophages recognizes a mucin-like molecule of house dust mite and suppresses mite-induced dermatitis.
https://immunology.sciencemag.org/content/4/42/eaax6908
1176 Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2.
https://immunology.sciencemag.org/content/4/42/eaav7501
1175 Chimeric antigen receptor (CAR) T cells engineered to overexpress the canonical AP-1 transcription factor c-Jun are resistant to T cell exhaustion, and provide enhanced therapeutic benefit in mouse tumour models.
https://www.nature.com/articles/s41586-019-1805-z
1174 A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses.
https://science.sciencemag.org/content/366/6470/eaax4380
1173 Screening of a library of bile acid metabolites revealed two derivatives of lithocholic acid that act as regulators of T helper cells that express IL-17a and regulatory T cells, thus influencing host immune responses.
https://www.nature.com/articles/s41586-019-1785-z
1172 A high-affinity human PD-1/PD-L2 complex informs avenues for small-molecule immune checkpoint drug discovery.
https://www.pnas.org/content/116/49/24500
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