457 CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells.
http://jem.rupress.org/content/210/12/2523.abstract
456 Rescue of a primary myelofibrosis model by retinoid-antagonist therapy.
http://www.pnas.org/content/110/47/18820.abstract
455 Platelet-targeted gene therapy with human factor VIII establishes haemostasis in dogs with haemophilia A.
http://www.nature.com/ncomms/2013/131119/ncomms3773/full/ncomms3773.html
454 Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia.
http://www.nature.com/nature/journal/v503/n7475/full/nature12746.html
453 Restoration of the Unfolded Protein Response in Pancreatic β Cells Protects Mice Against Type 1 Diabetes.
http://stm.sciencemag.org/content/5/211/211ra156.abstract
452 Enzymes secreted by a bacterial pathogen turn immune responses against themselves.
http://www.sciencemag.org/content/342/6160/863.abstract
451 Immunosignatures can predict vaccine efficacy.
http://www.pnas.org/content/110/46/18614.abstract
450 The transcription factor IRF4 is essential for TCR affinity–mediated metabolic programming and clonal expansion of T cells.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2710.html
449 Intergenic long noncoding RNAs (lincRNAs) regulate gene expression in various tissues. Zhao and colleagues identify 1,524 lincRNA clusters in thymocytes and mature T cell subsets and reveal dynamic and cell-specific patterns of lincRNA expression during T cell differentiation.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2712.html
448 Effector responses of NK cells occur via cytoxicity and cytokine secretion. Malarkannan and colleagues identify a signaling module that selectively controls the cytokine production of NK cells.
http://www.nature.com/ni/journal/v14/n11/abs/ni.2708.html
|
