487 Aberrant activation of human TH9 cells may contribute to inflammatory diseases of the skin.
http://stm.sciencemag.org/content/6/219/219ra8.abstract
486 Negatively charged immune-modifying microparticles bind to the scavenger receptor MARCO on inflammatory monocytes, resulting in their apoptosis and reduced inflammatory damage in a range of diseases.
http://stm.sciencemag.org/content/6/219/219ra7.abstract
485 The airway mucin Muc5b (but not Muc5ac) is required for mucociliary clearance, defence against bacterial infection in the airways and middle ear, and maintenance of immune homeostasis in the lungs; Muc5b deficiency causes accumulation of apoptotic macrophages, impairment of phagocytosis and reduced production of interleukin-23, leading to infection and inflammation.
http://www.nature.com/nature/journal/v505/n7483/full/nature12807.html
484 The success of the yellow fever vaccine is linked to the amino acid starvation pathway, which promotes adaptive immunity.
http://www.sciencemag.org/content/343/6168/313.abstract
483 Engineering an Effective Immune Adjuvant by Designed Control of Shape and Crystallinity of Aluminum Oxyhydroxide Nanoparticles.
http://pubs.acs.org/doi/abs/10.1021/nn404211j
482 Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages.
http://www.nature.com/ncomms/2014/140115/ncomms4039/full/ncomms4039.html
481 Hyperglycemia restricts the formation of new blood vessels by preventing VEGFR2 from responding to its angiogenic ligand VEGF.
http://stke.sciencemag.org/cgi/content/abstract/sigtrans;7/307/ra1
480 The immune system’s response to a mutant protein produced by an incipient cancer may help to explain an autoimmune disease.
http://www.sciencemag.org/content/343/6167/152.abstract
479 Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum.
http://www.pnas.org/content/111/1/427.abstract
478 The miR-126–VEGFR2 axis controls the innate response to pathogen-associated nucleic acids.
http://www.nature.com/ni/journal/v15/n1/abs/ni.2767.html
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